Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains
Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation DomainsActivation domains from a diverse array of mammalian and yeast transcription factors form phase-separated condensates with Mediator to activate gene expression.Activation domains from a diverse array of mammalian and yeast transcription factors form phase-separated condensates with Mediator to activate gene expression.Ann Boija, Isaac A. Klein, Benjamin R. Sabari, Alessandra Dall’Agnese, Eliot L. Coffey, Alicia V. Zamudio, Charles H. Li, Krishna Shrinivas, John C. Manteiga, Nancy M. Hannett, Brian J. Abraham, Lena K. Afeyan, Yang E. Guo, Jenna K. Rimel, Charli B. Fant, Jurian Schuijers, Tong Ihn Lee, Dylan J. Taatjes, Richard A. Younghttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2818%2931398-9%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignNovember 16, 2018
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