Macromolecular condensation organizes nucleolar sub-phases to set up a pH gradient

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Macromolecular condensation organizes nucleolar sub-phases to set up a pH gradientProteins containing blocks of charged amino acids in intrinsically disordered regions contribute to the layered organization of nucleoli and establish distinct pH environments in nuclear condensates.Proteins containing blocks of charged amino acids in intrinsically disordered regions contribute to the layered organization of nucleoli and establish […]

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Contrasting somatic mutation patterns in aging human neurons and oligodendrocytes

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Contrasting somatic mutation patterns in aging human neurons and oligodendrocytesBy employing single-cell whole-genome sequencing and integrating single-nucleus RNA-seq and single-nucleus ATAC-seq from the same individuals, this study uncovers distinct aging-related patterns of somatic mutation in human oligodendrocytes and neurons, which contribute to a deeper understanding of the mechanisms involved in human brain aging.By employing single-cell […]

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RNA damage compartmentalization by DHX9 stress granules

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RNA damage compartmentalization by DHX9 stress granulesDaughter cells arising from UV-exposed mother cells assemble stress granules that are marked by the dsRNA helicase DHX9. These stress granules sequester damaged intron RNA and activate several stress responses as a protective mechanism.Daughter cells arising from UV-exposed mother cells assemble stress granules that are marked by the dsRNA […]

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Sequans gets €11m from French government for 5G eRedCap R&D

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Sequans gets €11m from French government for 5G eRedCap R&DFrench IoT chipmaker Sequans Communications, which saw its $249m takeover by Japan-based Renesas Electronics come undone at the eleventh hour at the end of last month, has been granted €10.9 million from the French government to go towards development of 5G-based ‘reduced capability’ (RedCap) chips. The […]

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A gut-derived hormone regulates cholesterol metabolism

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A gut-derived hormone regulates cholesterol metabolismCholesin, a gut-secreted hormone induced by NPC1L1-mediated cholesterol uptake, binds to GPR146, inhibiting PKA-ERK1/2 signaling in the liver. This Cholesin-GPR146 axis suppresses SREBP2-controlled cholesterol synthesis, ultimately reducing circulating cholesterol levels.Cholesin, a gut-secreted hormone induced by NPC1L1-mediated cholesterol uptake, binds to GPR146, inhibiting PKA-ERK1/2 signaling in the liver. This Cholesin-GPR146 axis […]

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CommScope on open, converged 5G indoor networks

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CommScope on open, converged 5G indoor networksCommScope is bringing Open RAN indoors with updates to flagship DAS and small cell product Ahead of Mobile World Congress in Barcelona, CommScope announced support for third-party Open RAN Distributed Units (O-DUs) on its flagship all-digital ERA distributed antenna system (DAS) as well as its Open RAN-compliant ONECELL small […]

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Vodafone Idea aims 5G to account for 40% of revenue in two years

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Vodafone Idea aims 5G to account for 40% of revenue in two yearsVodafone Idea has recently completed its minimum rollout obligation towards 5G deployments in four telecom circles in India Indian carrier Vodafone Idea expects 5G technology to account for nearly 40% of its overall revenues in 24-to-30 months, according to local press reports. This […]

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Swisscom to acquire Vodafone Italia and merge it with Fastweb

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Swisscom to acquire Vodafone Italia and merge it with FastwebSwisscom said the acquisition of Vodafone Italia is expected to be completed during Q1 2025 Swiss carrier Swisscom confirmed it has entered into binding agreements with U.K carrier Vodafone Group for the acquisition of 100% of Vodafone Italia for EUR 8 billion ($8.71 billion) on a […]

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Reticulate Micro Joins WAVE Consortium as Founding Member

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Reticulate Micro Joins WAVE Consortium as Founding MemberReticulate Micro, Inc announced that it has joined the Waveform Architecture for Virtualized Ecosystems (WAVE) Consortium.Reticulate Micro, Inc announced that it has joined the Waveform Architecture for Virtualized Ecosystems (WAVE) Consortium.http://www.microwavejournal.com/rss/topic/3369-industry-newsIndustry Newshttps://www.microwavejournal.com/articles/41674-reticulate-micro-joins-wave-consortium-as-founding-memberPowered by WPeMatico

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