Mapping the cellular biogeography of human bone marrow niches using single-cell transcriptomics and proteomic imaging

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Mapping the cellular biogeography of human bone marrow niches using single-cell transcriptomics and proteomic imagingThis study employs scRNA-seq and CODEX multiplexed imaging to elucidate the cellular and spatial architecture of the human bone marrow microenvironment. Rare non-hematopoietic cells are enriched and profiled. Cellular neighborhoods and cell-cell interactions are revealed through integrative analysis of the multiomics data.This study employs scRNA-seq and CODEX multiplexed imaging to elucidate the cellular and spatial architecture of the human bone marrow microenvironment. Rare non-hematopoietic cells are enriched and profiled. Cellular neighborhoods and cell-cell interactions are revealed through integrative analysis of the multiomics data.Shovik Bandyopadhyay, Michael P. Duffy, Kyung Jin Ahn, Jonathan H. Sussman, Minxing Pang, David Smith, Gwendolyn Duncan, Iris Zhang, Jeffrey Huang, Yulieh Lin, Barbara Xiong, Tamjid Imtiaz, Chia-Hui Chen, Anusha Thadi, Changya Chen, Jason Xu, Melissa Reichart, Zachary Martinez, Caroline Diorio, Chider Chen, Vinodh Pillai, Oraine Snaith, Derek Oldridge, Siddharth Bhattacharyya, Ivan Maillard, Martin Carroll, Charles Nelson, Ling Qin, Kai Tanhttps://www.cell.com/cell/fulltext/S0092-8674(24)00408-2?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignMay 7, 2024

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