Interval between prior SARS-CoV-2 infection and booster vaccination impacts magnitude and quality of antibody and B cell responsesFor COVID-19 mRNA vaccines, immunization with a booster dose elicits robust antibody and B-cell responses that are further increased if a breakthrough infection occurs after vaccination. In contrast, when infection occurs prior to booster vaccination, antibody and B-cell responses are muted closer to the infection time and achieve better levels as the time interval between infection and vaccination increases.For COVID-19 mRNA vaccines, immunization with a booster dose elicits robust antibody and B-cell responses that are further increased if a breakthrough infection occurs after vaccination. In contrast, when infection occurs prior to booster vaccination, antibody and B-cell responses are muted closer to the infection time and achieve better levels as the time interval between infection and vaccination increases.Clarisa M. Buckner, Lela Kardava, Omar El Merhebi, Sandeep R. Narpala, Leonid Serebryannyy, Bob C. Lin, Wei Wang, Xiaozhen Zhang, Felipe Lopes de Assis, Sophie E.M. Kelly, I-Ting Teng, Genevieve E. McCormack, Lauren H. Praiss, Catherine A. Seamon, M. Ali Rai, Heather Kalish, Peter D. Kwong, Michael A. Proschan, Adrian B. McDermott, Anthony S. Fauci, Tae-Wook Chun, Susan Moirhttps://www.cell.com/cell/fulltext/S0092-8674(22)01251-X?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignSeptember 27, 2022

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