Distinct transcriptome architectures underlying lupus establishment and exacerbationA large-scale transcriptome analysis of 27 immune cell types from systemic lupus erythematous patients and healthy controls reveals two distinct pathological signatures of disease establishment and exacerbation, which could be informative for drug target discovery.A large-scale transcriptome analysis of 27 immune cell types from systemic lupus erythematous patients and healthy controls reveals two distinct pathological signatures of disease establishment and exacerbation, which could be informative for drug target discovery.Masahiro Nakano, Mineto Ota, Yusuke Takeshima, Yukiko Iwasaki, Hiroaki Hatano, Yasuo Nagafuchi, Takahiro Itamiya, Junko Maeda, Ryochi Yoshida, Saeko Yamada, Aya Nishiwaki, Haruka Takahashi, Hideyuki Takahashi, Yuko Akutsu, Takeshi Kusuda, Hiroyuki Suetsugu, Lu Liu, Kwangwoo Kim, Xianyong Yin, So-Young Bang, Yong Cui, Hye-Soon Lee, Hirofumi Shoda, Xuejun Zhang, Sang-Cheol Bae, Chikashi Terao, Kazuhiko Yamamoto, Tomohisa Okamura, Kazuyoshi Ishigaki, Keishi Fujiohttps://www.cell.com/cell/fulltext/S0092-8674(22)00924-2?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignAugust 23, 2022

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