Defining the Design Principles of Skin Epidermis Postnatal GrowthDuring postnatal growth, tissues steadily grow until they achieve their final size. Looking at the interfollicular epidermis in mice, Dekoninck et al. find that progenitors present an excess of self-renewing division throughout the development. This imbalance, coupled with an ever-decreasing proliferation rate in both scale and interscale compartments, provides linear tissue expansion and maintenance of skin barrier function at the same time.During postnatal growth, tissues steadily grow until they achieve their final size. Looking at the interfollicular epidermis in mice, Dekoninck et al. find that progenitors present an excess of self-renewing division throughout the development. This imbalance, coupled with an ever-decreasing proliferation rate in both scale and interscale compartments, provides linear tissue expansion and maintenance of skin barrier function at the same time.Sophie Dekoninck, Edouard Hannezo, Alejandro Sifrim, Yekaterina A. Miroshnikova, Mariaceleste Aragona, Milan Malfait, Souhir Gargouri, Charlotte de Neunheuser, Christine Dubois, Thierry Voet, Sara A. Wickström, Benjamin D. Simons, Cédric Blanpainhttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2820%2930277-4%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignApril 7, 2020

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