Cytoneme signaling provides essential contributions to mammalian tissue patterningDuring neural tube development, cytonemes, specialized signaling filopodia, contribute to the dispersion of sonic hedgehog and WNT to ensure appropriate cell fate determination across ventral and dorsal morphogen signaling gradients. Dispatched facilitates endocytic recycling of sonic hedgehog to promote ligand entry into cytonemes.During neural tube development, cytonemes, specialized signaling filopodia, contribute to the dispersion of sonic hedgehog and WNT to ensure appropriate cell fate determination across ventral and dorsal morphogen signaling gradients. Dispatched facilitates endocytic recycling of sonic hedgehog to promote ligand entry into cytonemes.Eric T. Hall, Miriam E. Dillard, Elizabeth R. Cleverdon, Yan Zhang, Christina A. Daly, Shariq S. Ansari, Randall Wakefield, Daniel P. Stewart, Shondra M. Pruett-Miller, Alfonso Lavado, Alex F. Carisey, Amanda Johnson, Yong-Dong Wang, Emma Selner, Michael Tanes, Young Sang Ryu, Camenzind G. Robinson, Jeffrey Steinberg, Stacey K. Ogdenhttps://www.cell.com/cell/fulltext/S0092-8674(23)01333-8?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignJanuary 3, 2024

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