C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infectionBeyond liver-derived complement component C5, locally produced C5 is a critical mediator of antifungal defense in infected tissues, and this finding explains the susceptibility of patients to systemic Candida infection after C5 inhibition therapy.Beyond liver-derived complement component C5, locally produced C5 is a critical mediator of antifungal defense in infected tissues, and this finding explains the susceptibility of patients to systemic Candida infection after C5 inhibition therapy.Jigar V. Desai, Dhaneshwar Kumar, Tilo Freiwald, Daniel Chauss, Melissa D. Johnson, Michael S. Abers, Julie M. Steinbrink, John R. Perfect, Barbara Alexander, Vasiliki Matzaraki, Brendan D. Snarr, Marissa A. Zarakas, Vasileios Oikonomou, Lakmali M. Silva, Raju Shivarathri, Emily Beltran, Luciana Negro Demontel, Luopin Wang, Jean K. Lim, Dylan Launder, Heather R. Conti, Muthulekha Swamydas, Micah T. McClain, Niki M. Moutsopoulos, Majid Kazemian, Mihai G. Netea, Vinod Kumar, Jörg Köhl, Claudia Kemper, Behdad Afzali, Michail S. Lionakishttps://www.cell.com/cell/fulltext/S0092-8674(23)00465-8?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignMay 23, 2023

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