Dual-role transcription factors stabilize intermediate expression levels

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Dual-role transcription factors stabilize intermediate expression levelsCondensate-forming dual-action TFs are identified that reduce high expression but increase low expression of target genes to achieve stable intermediate levels, which is critical for the regulation of poised developmental gene programs.Condensate-forming dual-action TFs are identified that reduce high expression but increase low expression of target genes to achieve stable intermediate levels, which is critical for the regulation of poised developmental gene programs.Jinnan He, Xiangru Huo, Gaofeng Pei, Zeran Jia, Yiming Yan, Jiawei Yu, Haozhi Qu, Yunxin Xie, Junsong Yuan, Yuan Zheng, Yanyan Hu, Minglei Shi, Kaiqiang You, Tingting Li, Tianhua Ma, Michael Q. Zhang, Sheng Ding, Pilong Li, Yinqing Lihttps://www.cell.com/cell/fulltext/S0092-8674(24)00314-3?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignApril 17, 2024

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