Multiscale drug screening for cardiac fibrosis identifies MD2 as a therapeutic target

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Multiscale drug screening for cardiac fibrosis identifies MD2 as a therapeutic targetA multiscale drug discovery platform integrating human induced pluripotent stem cells, 3D-engineered heart tissues, and animal models identifies artesunate as a safe and potent antifibrotic compound.A multiscale drug discovery platform integrating human induced pluripotent stem cells, 3D-engineered heart tissues, and animal models identifies artesunate as a safe and potent antifibrotic compound.Hao Zhang, Phung N. Thai, Rabindra V. Shivnaraine, Lu Ren, Xuekun Wu, Dirk H. Siepe, Yu Liu, Chengyi Tu, Hye Sook Shin, Arianne Caudal, Souhrid Mukherjee, Jeremy Leitz, Wilson Tan Lek Wen, Wenqiang Liu, Wenjuan Zhu, Nipavan Chiamvimonvat, Joseph C. Wuhttps://www.cell.com/cell/fulltext/S0092-8674(24)01092-4?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignOctober 16, 2024

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