Multiple independent acquisitions of ACE2 usage in MERS-related coronaviruses

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Multiple independent acquisitions of ACE2 usage in MERS-related coronavirusesTwo coronaviruses related to MERS-CoV, which infect European Pipistrellus bats, have been found to use ACE2 as their receptor. These viruses target an ACE2 surface region distant from those recognized by other known ACE2-using coronaviruses, highlighting convergent evolution in their adaptation to utilize ACE2.Two coronaviruses related to MERS-CoV, which infect European Pipistrellus bats, have been found to use ACE2 as their receptor. These viruses target an ACE2 surface region distant from those recognized by other known ACE2-using coronaviruses, highlighting convergent evolution in their adaptation to utilize ACE2.Cheng-Bao Ma, Chen Liu, Young-Jun Park, Jingjing Tang, Jing Chen, Qing Xiong, Jimin Lee, Cameron Stewart, Daniel Asarnow, Jack Brown, M. Alejandra Tortorici, Xiao Yang, Ye-Hui Sun, Yuan-Mei Chen, Xiao Yu, Jun-Yu Si, Peng Liu, Fei Tong, Mei-Ling Huang, Jing Li, Zheng-Li Shi, Zengqin Deng, David Veesler, Huan Yanhttps://www.cell.com/cell/fulltext/S0092-8674(24)01474-0?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignFebruary 8, 2025

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