Genome-wide data from medieval German Jews show that the Ashkenazi founder event pre-dated the 14th centuryGenome-wide data was generated for 33 individuals whose skeletons were rescued from a late medieval Jewish cemetery in Erfurt, Germany. Medieval German Jews had similar genetic ancestry to modern Ashkenazi Jews but were more genetically heterogeneous, likely divided into two or more distinct groups. The medieval Jews showed evidence of an extreme founder event, including high levels of runs of homozygosity and distinctive genetic variants shared with modern Ashkenazi Jews.Genome-wide data was generated for 33 individuals whose skeletons were rescued from a late medieval Jewish cemetery in Erfurt, Germany. Medieval German Jews had similar genetic ancestry to modern Ashkenazi Jews but were more genetically heterogeneous, likely divided into two or more distinct groups. The medieval Jews showed evidence of an extreme founder event, including high levels of runs of homozygosity and distinctive genetic variants shared with modern Ashkenazi Jews.Shamam Waldman, Daniel Backenroth, Éadaoin Harney, Stefan Flohr, Nadia C. Neff, Gina M. Buckley, Hila Fridman, Ali Akbari, Nadin Rohland, Swapan Mallick, Iñigo Olalde, Leo Cooper, Ariel Lomes, Joshua Lipson, Jorge Cano Nistal, Jin Yu, Nir Barzilai, Inga Peter, Gil Atzmon, Harry Ostrer, Todd Lencz, Yosef E. Maruvka, Maike Lämmerhirt, Alexander Beider, Leonard V. Rutgers, Virginie Renson, Keith M. Prufer, Stephan Schiffels, Harald Ringbauer, Karin Sczech, Shai Carmi, David Reichhttps://www.cell.com/cell/fulltext/S0092-8674(22)01378-2?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignDecember 1, 2022

Powered by WPeMatico