Detection and analysis of complex structural variation in human genomes across populations and in brains of donors with psychiatric disorders

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Detection and analysis of complex structural variation in human genomes across populations and in brains of donors with psychiatric disordersARC-SV enables highly accurate detection and characterization of localized complex rearrangements of multiple DNA segments. Applying ARC-SV across human populations and brain cohorts uncovers connections between complex structural variantion and human-specific evolution, neural genes, and major psychiatric disorders.ARC-SV enables highly accurate detection and characterization of localized complex rearrangements of multiple DNA segments. Applying ARC-SV across human populations and brain cohorts uncovers connections between complex structural variantion and human-specific evolution, neural genes, and major psychiatric disorders.Bo Zhou, Joseph G. Arthur, Hanmin Guo, Taeyoung Kim, Yiling Huang, Reenal Pattni, Tao Wang, Soumya Kundu, Jay X.J. Luo, HoJoon Lee, Daniel C. Nachun, Carolin Purmann, Emma M. Monte, Annika K. Weimer, Ping-Ping Qu, Minyi Shi, Lixia Jiang, Xinqiong Yang, John F. Fullard, Jaroslav Bendl, Kiran Girdhar, Minsu Kim, Xi Chen, PsychENCODE Consortium, William J. Greenleaf, Laramie Duncan, Hanlee P. Ji, Xiang Zhu, Giltae Song, Stephen B. Montgomery, Dean Palejev, Heinrich zu Dohna, Panos Roussos, Anshul Kundaje, Joachim F. Hallmayer, Michael P. Snyder, Wing H. Wong, Alexander E. Urbanhttps://www.cell.com/cell/fulltext/S0092-8674(24)01032-8?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignOctober 1, 2024

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