Cyclic-dinucleotide-induced filamentous assembly of phospholipases governs broad CBASS immunityPhospholipase effectors of the CBASS system assemble from an inactive dimeric state into active higher-order filamentous oligomers upon sensing cyclic dinucleotides, facilitating membrane disruption and subsequent cell lysis to prevent phage propagation.Phospholipase effectors of the CBASS system assemble from an inactive dimeric state into active higher-order filamentous oligomers upon sensing cyclic dinucleotides, facilitating membrane disruption and subsequent cell lysis to prevent phage propagation.Jingge Wang, Zhao Li, Hao Lang, Wenfeng Fu, Yina Gao, Sen Yin, Panpan Sun, Zhaolong Li, Jiafeng Huang, Songqing Liu, Yun Zhu, Fei Sun, Dong Li, Pu Gao, Ang Gaohttps://www.cell.com/cell/fulltext/S0092-8674(25)00457-X?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignMay 9, 2025

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