A replisome-associated histone H3-H4 chaperone required for epigenetic inheritanceA histone H3-H4 binding domain in the Mrc1/CLASPIN component of the replisome is required for parental histone transfer and epigenetic inheritance of heterochromatin. The predicted location of Mrc1 and other histone-binding proteins in the replisome suggests a path for parental histone transfer to newly synthesized DNA.A histone H3-H4 binding domain in the Mrc1/CLASPIN component of the replisome is required for parental histone transfer and epigenetic inheritance of heterochromatin. The predicted location of Mrc1 and other histone-binding proteins in the replisome suggests a path for parental histone transfer to newly synthesized DNA.Juntao Yu, Yujie Zhang, Yimeng Fang, Joao A. Paulo, Dadmehr Yaghoubi, Xu Hua, Gergana Shipkovenska, Takenori Toda, Zhiguo Zhang, Steven P. Gygi, Songtao Jia, Qing Li, Danesh Moazedhttps://www.cell.com/cell/fulltext/S0092-8674(24)00766-9?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignAugust 2, 2024

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