Omicron’s Message on Vaccines: Boosting Begets Breadth

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Omicron’s Message on Vaccines: Boosting Begets BreadthIn this issue of Cell, three studies confirm that SARS-CoV-2 Omicron strongly evades a key immune defense—neutralizing antibodies. However, while one- or two-dose vaccine regimens fail to induce anti-Omicron neutralizing antibodies, a homologous 3rd-dose booster rescues neutralization function in a way that highlights the adaptability of immune memory, where recalled immune memory extends antibody reach across-SARS-CoV-2 variants.In this issue of Cell, three studies confirm that SARS-CoV-2 Omicron strongly evades a key immune defense—neutralizing antibodies. However, while one- or two-dose vaccine regimens fail to induce anti-Omicron neutralizing antibodies, a homologous 3rd-dose booster rescues neutralization function in a way that highlights the adaptability of immune memory, where recalled immune memory extends antibody reach across-SARS-CoV-2 variants.Duane R. Wesemannhttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2822%2900006-X%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignJanuary 14, 2022

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